Nonstop flights from Philadelphia to Greenville
American Airlines flies this route 2 to 3 times a day.
PHLPhiladelphia International
514 mi · 20 flights a week
GSPGreenville-Spartanburg International
When they leave
Philadelphia time8:20a5:48pFirst departure 8:20 AM, last 5:48 PM
One morning flight at 8:20 AM, then one afternoon flight at 12:37 PM, then one evening flight at 5:48 PM.
Every flight
Earliest first
Schedules last checked Sep 20, 2026. Times are local.
Flying from Philadelphia to Greenville
American Airlines is the only airline flying nonstop from Philadelphia to Greenville, 2 to 3 times a day on the Embraer ERJ-145 and CRJ 900.
There are 2 or 3 flights every day of the week. The first arrival in Greenville is at 10:24 AM and the last at 7:45 PM. The flight covers 514 miles.
Flying back, Greenville to Philadelphia has 20 nonstop flights a week.
Return flights
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Find the cheapest day to fly from Philadelphia to Greenville.
Schedules as of Oct 9, 2026.