Nonstop flights from Myrtle Beach to Chicago

Southwest Airlines flies this route daily until Oct 30, then again from Nov 21.

MYRMyrtle Beach International

738 mi · 7 flights a week

MDWChicago Midway International

MYRMDW

When they leave

Myrtle Beach time

8:10a1:40pFirst departure 8:10 AM, last 1:40 PM

One morning flight at 8:10 AM, then one afternoon flight at 1:40 PM.

Every flight

Earliest first

8:10 AM→9:15 AMSouthwest AirlinesUntil Oct 30, back Nov 21Boeing 737 MAX 8Mon, Tue, Wed, Thu, Fri, Sun
1:40 PM→2:45 PMSouthwest AirlinesUntil Oct 30, back Nov 21Boeing 737-700Sat

Schedules last checked Sep 22, 2026. Times are local.

Flying from Myrtle Beach to Chicago

Southwest Airlines is the only airline flying nonstop from Myrtle Beach to Chicago, daily on the Boeing 737 MAX 8 and Boeing 737-700.

The first arrival in Chicago is at 9:15 AM and the last at 2:45 PM. The flight covers 738 miles.

Flying back, Chicago to Myrtle Beach has 7 nonstop flights a week. From Myrtle Beach, O'Hare (ORD) is the other Chicago area airport with nonstop flights, 15 a week.