Nonstop flights from Manchester to Chicago
American Airlines flies this route 3 times a day until Oct 31.
MHTManchester-Boston Regional
841 mi · 21 flights a week
ORDChicago O'Hare International
When they leave
Manchester time7:16a5:41pFirst departure 7:16 AM, last 5:41 PM
One morning flight at 7:16 AM, then one afternoon flight at 12:12 PM, then one evening flight at 5:41 PM. Every flight runs daily.
Every flight
Earliest first
Schedules last checked Sep 20, 2026. Times are local.
Flying from Manchester to Chicago
American Airlines is the only airline flying nonstop from Manchester to Chicago, 3 times a day on the Embraer 170.
The first arrival in Chicago is at 9:10 AM and the last at 7:50 PM. The flight covers 841 miles.
Flying back, Chicago to Manchester has 21 nonstop flights a week. From Manchester, Midway (MDW) is the other Chicago area airport with nonstop flights, 14 a week.
Return flights
Every Chicago airport
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Find the cheapest day to fly from Manchester to Chicago.
Schedules as of Oct 9, 2026.