Nonstop flights from Chicago to Charleston
Southwest Airlines flies this route 1 to 2 times a day.
MDWChicago Midway International
746 mi · 11 flights a week
CHSCharleston International
When they leave
Chicago time7:35a6:15pFirst departure 7:35 AM, last 6:15 PM
Two in the morning, 7:35 AM to 8:15 AM, then two in the evening, 6:05 PM to 6:15 PM.
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Schedules last checked Sep 19, 2026. Times are local.
Flying from Chicago to Charleston
Southwest Airlines is the only airline flying nonstop from Chicago to Charleston, 1 to 2 times a day on the Boeing 737 MAX 8 and Boeing 737.
There are 1 or 2 flights every day of the week. The first arrival in Charleston is at 10:55 AM and the last at 9:25 PM. The flight covers 746 miles.
Flying back, Charleston to Chicago has 11 nonstop flights a week. O'Hare (ORD) also has nonstop flights to Charleston, 42 a week.
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Schedules as of Oct 9, 2026.