Nonstop flights from Harrisburg to Chicago

2 airlines fly this route, with up to 7 flights a day.

MDTHarrisburg International

593 mi · 49 flights a week

ORDChicago O'Hare International

MDTORD

When they leave

Harrisburg time

6:00a7:31pFirst departure 6:00 AM, last 7:31 PM

Three in the morning, 6:00 AM to 10:40 AM, then two in the afternoon, 1:25 PM to 2:17 PM, then two in the evening, 5:54 PM to 7:31 PM. Every flight runs daily.

Every flight

Earliest first

6:00 AM→7:21 AMAmerican AirlinesEmbraer 175Daily
6:30 AM→7:41 AMUnited AirlinesBoeing 737Daily
10:40 AM→11:53 AMUnited AirlinesCRJ 700Daily
1:25 PM→2:35 PMAmerican AirlinesAirbus A319Daily
2:17 PM→3:33 PMUnited AirlinesEmbraer 175Daily
5:54 PM→7:05 PMUnited AirlinesBoeing 737Daily
7:31 PM→9:00 PMAmerican AirlinesAirbus A319Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Harrisburg to Chicago

United Airlines flies most often, 4 times a day on the Boeing 737, CRJ 700 and Embraer 175. American Airlines flies 3 times a day on the Airbus A319 and Embraer 175.

There are 7 flights every day of the week. The first arrival in Chicago is at 7:21 AM and the last at 9:00 PM. The flight covers 593 miles.

Flying back, Chicago to Harrisburg has 50 nonstop flights a week.