Nonstop flights from Rome to Istanbul
Turkish Airlines flies this route 4 times a day.
FCORome Leonardo da Vinci International
852 mi · 28 flights a week
ISTIstanbul
When they leave
Rome time7:05a8:05pFirst departure 7:05 AM, last 8:05 PM
Two in the morning, 7:05 AM to 10:55 AM, then one afternoon flight at 3:35 PM, then one evening flight at 8:05 PM. Every flight runs daily.
Every flight
Earliest first
Schedules last checked Sep 8, 2026. Times are local.
Flying from Rome to Istanbul
Turkish Airlines is the only airline flying nonstop from Rome to Istanbul, 4 times a day on the Airbus A321, Airbus A350 and Boeing 787.
The first arrival in Istanbul is at 10:45 AM and the last at 11:35 PM. The flight covers 852 miles.
Flying back, Istanbul to Rome has 28 nonstop flights a week.
Return flights
More from Rome
Find the cheapest day to fly from Rome to Istanbul.
Schedules as of Oct 9, 2026.