Nonstop flights from Key West to Charlotte
American Airlines flies this route 2 to 3 times a day.
EYWKey West International
739 mi · 15 flights a week
CLTCharlotte Douglas International
When they leave
Key West time1:50p7:14pFirst departure 1:50 PM, last 7:14 PM
Two in the afternoon, 1:50 PM to 4:50 PM, then one evening flight at 7:14 PM.
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Schedules last checked Sep 22, 2026. Times are local.
Flying from Key West to Charlotte
American Airlines is the only airline flying nonstop from Key West to Charlotte, 2 to 3 times a day on the Embraer 175 and Airbus A319.
Flights run every day of the week, 3 on Sundays and 2 on the other days. The first arrival in Charlotte is at 4:14 PM and the last at 9:49 PM. The flight covers 739 miles.
Flying back, Charlotte to Key West has 15 nonstop flights a week.
Return flights
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Schedules as of Oct 9, 2026.