Nonstop flights from Charlotte to Florence
American Airlines flies this route twice a day.
CLTCharlotte Douglas International
99 mi · 14 flights a week
FLOFlorence Regional
When they leave
Charlotte time1:52p9:53pFirst departure 1:52 PM, last 9:53 PM
One afternoon flight at 1:52 PM, then one evening flight at 9:53 PM. Every flight runs daily.
Every flight
Earliest first
Schedules last checked Sep 19, 2026. Times are local.
Flying from Charlotte to Florence
American Airlines is the only airline flying nonstop from Charlotte to Florence, twice a day on the Embraer ERJ-145.
The first arrival in Florence is at 2:56 PM and the last at 10:59 PM. The flight covers 99 miles.
Flying back, Florence to Charlotte has 14 nonstop flights a week.
Return flights
Find the cheapest day to fly from Charlotte to Florence.
Schedules as of Oct 9, 2026.