Nonstop flights from Buffalo to Chicago

2 airlines fly this route, with up to 7 flights a day.

BUFBuffalo Niagara International

472 mi · 49 flights a week

ORDChicago O'Hare International

BUFORD

When they leave

Buffalo time

5:11a6:09pFirst departure 5:11 AM, last 6:09 PM

Four in the morning, 5:11 AM to 10:30 AM, then one afternoon flight at 1:51 PM, then two in the evening, 5:58 PM to 6:09 PM.

Every flight

Earliest first

5:11 AM→6:05 AMAmerican AirlinesUntil Jan 17, 2027, back Mar 19, 2027Embraer 175Daily
6:54 AM→8:00 AMUnited AirlinesEmbraer 175Tue
6:55 AM→7:55 AMUnited AirlinesBoeing 737Mon, Wed, Thu, Fri, Sat, Sun
10:30 AM→11:29 AMUnited AirlinesBoeing 737Daily
10:30 AM→11:35 AMAmerican AirlinesUntil Jan 17, 2027, back Mar 19, 2027Embraer 175Daily
1:51 PM→2:55 PMUnited AirlinesCRJ 700Daily
5:58 PM→7:00 PMUnited AirlinesBoeing 737Daily
6:09 PM→7:27 PMAmerican AirlinesUntil Jan 17, 2027, back Mar 19, 2027Airbus A319Daily

Schedules last checked Sep 19, 2026. Times are local.

Flying from Buffalo to Chicago

United Airlines flies most often, 4 times a day on the Boeing 737, CRJ 700 and Embraer 175. American Airlines flies 3 times a day on the Embraer 175 and Airbus A319.

There are 7 flights every day of the week. The first arrival in Chicago is at 6:05 AM and the last at 7:27 PM. The flight covers 472 miles.

American Airlines flies it until Jan 17, 2027 and is back on Mar 19, 2027.

Flying back, Chicago to Buffalo has 38 nonstop flights a week. From Buffalo, Midway (MDW) is the other Chicago area airport with nonstop flights, 20 a week.